EXPRESSION ALTERATION OF MICRORNAS IN NUCLEUS ACCUMBENS IS ASSOCIATED WITH CHRONIC STRESS AND ANTIDEPRESSANT TREATMENT IN RATS

Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats

Abstract Background Nucleus Accumbens (NAc) is a vital brain region for the process of reward and stress, whereas microRNA plays a crucial role in depression pathology.However, the abnormality of NAc miRNA expression during the stress-induced depression and antidepressant treatment, as well as its biological significance, are still unknown.Methods

read more

Global Optimization of Nonlinear Blend-Scheduling Problems

The scheduling of gasoline-blending operations is an important problem in the oil refining industry.This problem not only exhibits the combinatorial nature that is intrinsic buy shredder ptc to scheduling problems, but also non-convex nonlinear behavior, due to the blending of various materials with different quality properties.In this work, a glob

read more


Reference seismic crustal model of the Dinarides

Continental collision zones are structurally one of the most heterogeneous areas intermixing various different units within a relatively small space.A good example of this is the Dinarides, a mountain chain situated in the central Mediterranean, where thick carbonates cover older crystalline basement units and remnants of subducted oceanic crust.Th

read more